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180246

Sigma-Aldrich

2-Naphthoesäure

98%

Synonym(e):

2-Naphthalincarbonsäure

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About This Item

Lineare Formel:
C10H7CO2H
CAS-Nummer:
93-09-4
Molekulargewicht:
172.18
Beilstein:
972039
EG-Nummer:
202-217-8
MDL-Nummer:
MFCD00004101
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24850857
NACRES:
NA.22

Qualitätsniveau

100

Assay

98%

Form

powder

mp (Schmelzpunkt)

185-187 °C (lit.)

Löslichkeit

alcohol: soluble
diethyl ether: soluble
hot water: slightly soluble

SMILES String

OC(=O)c1ccc2ccccc2c1

InChI

1S/C11H8O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,12,13)

InChIKey

UOBYKYZJUGYBDK-UHFFFAOYSA-N

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Allgemeine Beschreibung

2-Naphthoic acid (NPA) is a noncompetitive N-methyl-D-aspartate (NMDA) receptor inhibitor. The fluorescence spectra and electronic absorption of 2-naphthoic acid was studied.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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6-Bromo-2-naphthoic acid AldrichCPR

Sigma-Aldrich

CDS004635

6-Bromo-2-naphthoic acid

2-Naphthalinmethanol 98%

Sigma-Aldrich

187313

2-Naphthalinmethanol

2-Hydroxy-1-Naphthoesäure 98%

Sigma-Aldrich

H45809

2-Hydroxy-1-Naphthoesäure

Naptalam PESTANAL®, analytical standard

Supelco

33371

Naptalam

An electronic spectral study of the influence of thermal and electronic processes on the determination of the excited singlet-state dissociation constants of 1-and 2-naphthoic acid.
Kovi PJ and Schulman SG.
Analytica Chimica Acta, 63(1), 39-52 (1973)
Han Yu et al.
Molecular pharmacology, 84(4), 541-550 (2013-07-23)
N-Methyl-D-aspartate (NMDA) receptors mediate excitatory synaptic transmission in the central nervous system and play important roles in synaptic development and plasticity, but also mediate glutamate neurotoxicity. Recently, 2-naphthoic acid (NPA) and its derivatives have been identified as allosteric, noncompetitive NMDA
V Krishnakumar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(1), 201-209 (2007-09-08)
The solid phase mid FTIR and FT Raman spectra of 2-naphthoic acid (NA) and 6-bromo-2-naphthoic acid (BNA) have been recorded in the regions 4000-400 cm(-1) and 3500-100 cm(-1), respectively. The fundamental vibrational frequencies and intensities of the vibrational bands were
M J Melancon et al.
Drug metabolism and disposition: the biological fate of chemicals, 10(2), 128-133 (1982-03-01)
Urine was collected from four female rats for 3 days after two subcutaneous injections with 0.3 mg of 2-methyl[8-14C]naphthalene per kg. Of the 14C injected, 55% was found in the urine. The urine was solvent-fractionated into a toluene fraction (4.9%
Blaise Mathias Costa et al.
Neuropharmacology, 62(4), 1730-1736 (2011-12-14)
Over-activation of N-methyl-d-aspartate (NMDA) receptors is critically involved in many neurological conditions, thus there has been considerable interest in developing NMDA receptor antagonists. We have recently identified a series of naphthoic and phenanthroic acid compounds that allosterically modulate NMDA receptors
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