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  • The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase.

The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase.

Pharmeuropa scientific notes (2007-08-11)
S P Dixon, A Lodi, J H M Miller, G G Skellern
ZUSAMMENFASSUNG

An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.

MATERIALIEN
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Produktbeschreibung

Dibenzosuberon, European Pharmacopoeia (EP) Reference Standard